The highlights/important parts of her life are..
Father got into a critical accident and was saved by doctor. Evoking Melanthe's wish to be a doctor.
She managed from that point to be a straight A student, and got some scholarships to aid in her quest.
She eventually was accepted into Harvard, where she met and began to date the Dean of the school's son. After a couple months, her boyfriend became abusive.
Melanthe dealt with the abuse for nearly a year. Finally she snapped and struck back out at him, then fled.
Melanthe quickly transferred over to Miskatonic, figuring it to be remote enough to be safe from her rich ex.
Since then, she has had some crazy things happen..
She heard a seductive song that nearly drew her into the sea. She was stopped by some bystanders.
She was kidnapped and buried alive (unknown to her by Outlook), and mentally tortured with sounds of dark laughing as she laid trapped in her coffin.